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| Introduction: |
A major aldehydic product formed by peroxidation of ω-6-unsaturated fatty acids that is regarded as a specific marker of lipid peroxidation. Inhibits proliferation and induces differentiation of HL-60 human leukemic cells. Also induces cell death in murine alveolar macrophages. An inhibitor of state 3 respiration at micromolar levels that causes a transient increase in cytosolic Ca2+. Irreversibly inhibits Na+-K+-ATPase activity (IC50=120 mM).
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| Form: |
Liquid. Supplied in ethanol.
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| Amount per kit: |
1 mg
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| CAS: |
75899-68-2
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| RETCS: |
RA8510000
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| Weight: |
156.2
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| Molecular Formula: |
C9H16O2
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| Purity: |
>=98% by HPLC
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| Solubility: |
Ethanol
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| Storage: |
Deep freeze. This product is stable for 3 years as supplied.
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| References: |
1.Carini, R., et al. 1996. Biochem. Biophys. Res. Commun. 218, 772.
2.Li, L., et al. 1996. Toxicol. Appl. Pharmacol. 139, 135.
3.Siems, W.G., et al. 1996. Free Radic. Res. 20, 215.
4.Ullrich, O., et al. 1996. Free Radic. Res. 24, 421.
5.van Kuijk, F.J.G.M., et al. 1995. Anal. Biochem. 224, 420.
6.Esterbauer, H., et al. 1991. Free Radic. Biol. Med. 11, 81.
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**For research use only. Not for use in diagnostic procedures.** |